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I’m excited to share that I have started a new position at the Center for Quantitative Genetics and Genomics (QGG) at Aarhus University. Looking forward to this new chapter and the exciting research, teaching, and collaborations ahead!
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I’m happy to share that I have two new publications out, spanning statistical emulation and rapid adaptation.
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Our latest study looks at how P-element insertions affect fitness in fruit flies. Using experimental evolution and machine learning, we tracked how these transposable elements spread—and found that most new insertions are harmful and selected against. Excited to see this work published in Genome Biology! Check it out here.
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I gave a speed talk at the Arhus Festival of Research about my work on transposable element invasions in Drosophila. Couldn’t make it? A short article about my talk is available online .
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New paper out in Theoretical Population Biology! We investigate spatial structure in disease models, revealing when spatial heterogeneity must be considered for accurate predictions and how it impacts key epidemiological outcomes—bridging theory and simulations for more realistic epidemic modeling. For a plain-language summary, check out the blog post under the “Publications” tab.
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I am delighted to start my new position as AIAS-AUFF fellow at the Aarhus Institute of Advanced Science. In my project, I will use individual simulations and statistical frameworks to study how adaptation works across time and space.
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The department of Biomathematics was actively participating in the Long Night of Research in Vienna - a biannual national science outreach event. We discussed with the visitors our research projects, explored the emergence of collective behavior, and simulated epidemics with playing cards. Couldn’t make it? All our material is avaliable online!
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Kiran Chandrasekher has been arwarded a prestigious Barry Goldwater Scholarship! Kiran is an undergraduate researcher that investigates with me the importance of seasonality and human movement on dengue dynamics. Congrats Kiran - so well deserved!
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New paper out in Nucleic Acids Research! We use Evolve & Resequence to measure purifying selection & insertion bias on an active TE in Drosophila simulans. Check out the “Publications” tab for more details.
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The first postdoc preprint is available: “Catching a wave: on the suitability of traveling-wave solutions in epidemiological modeling”! We use diffusion-theory and individual-based models to figure out when exactly limited individual dispersal starts to affect disease dynamics, such that spatial structure needs to be considered. The preprint is available on bioRxiv. Check out the “Publications” tab for more details.
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New paper out in Science (including cool cover art)! “Deep cis-regulatory homology of the butterfly wing pattern ground plan” studies the evolution and role of cis-regulatory elements of a patterning gene in five different butterfly species. Fun cross-disciplinary collaboration with Anyi Mazo-Vargos, Robert Reed, and others. Check out this Twitter thread of Anyi for more details!
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New paper out in eLife! “Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations” sheds light on the (off-target) fitness effects of CRISPR/Cas9 and their potential implications on gene drives and beyond! Exciting work in collaboration with Jackson Champer, Philipp Messer, Andrew Clark, and many others. Check out the “Publications” section for more details.
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New paper out in G3! Happy to announce that “A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles” is out now in G3. Spearheaded by talented student Emily Yang, we introduce a suppression drive that avoids the formation of functional resistance alleles in experimental Drosophila populations. Check out the “Publications” section for more details.
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hello world. The “Spatial Structure” project has officially begun. Funded by the Marie Skłodowska-Curie Actions programme, this project aims towards improved agent-based models of mosquito transmitted diseases. More detail about the “Spatial Structure” project can be found under “Research”.