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Kiran Chandrasekher has been arwarded a prestigious Barry Goldwater Scholarship! Kiran is an undergraduate researcher that investigates with me the importance of seasonality and human movement on dengue dynamics. Congrats Kiran - so well deserved!
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New paper out in Nucleic Acids Research! We use Evolve & Resequence to measure purifying selection & insertion bias on an active TE in Drosophila simulans. Check out the “Publications” tab for more details.
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The first postdoc preprint is available: “Catching a wave: on the suitability of traveling-wave solutions in epidemiological modeling”! We use diffusion-theory and individual-based models to figure out when exactly limited individual dispersal starts to affect disease dynamics, such that spatial structure needs to be considered. The preprint is available on bioRxiv. Check out the “Research” tab for more details.
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New paper out in Science (including cool cover art)! “Deep cis-regulatory homology of the butterfly wing pattern ground plan” studies the evolution and role of cis-regulatory elements of a patterning gene in five different butterfly species. Fun cross-disciplinary collaboration with Anyi Mazo-Vargos, Robert Reed, and others. Check out this Twitter thread of Anyi for more details!
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New paper out in eLife! “Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations” sheds light on the (off-target) fitness effects of CRISPR/Cas9 and their potential implications on gene drives and beyond! Exciting work in collaboration with Jackson Champer, Philipp Messer, Andrew Clark, and many others. Check out the “Publications” section for more details.
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New paper out in G3! Happy to announce that “A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles” is out now in G3. Spearheaded by talented student Emily Yang, we introduce a suppression drive that avoids the formation of functional resistance alleles in experimental Drosophila populations. Check out the “Publications” section for more details.
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hello world. The “Spatial Structure” project has officially begun. Funded by the Marie Skłodowska-Curie Actions programme, this project aims towards improved agent-based models of mosquito transmitted diseases. More detail about the “Spatial Structure” project can be found under “Research”.